BDBM594068 Synthesis of (R)-2,3,5-trimethyl-6-(12,12,12-trifluoro-3-hydroxy-3-methyldodecyl)cyclo-hexa-2,5-diene-1,4-dione ::US11584728, Compound N::US12049455, Compound N::US20230303506, Compound N::US20240400529, Compound N

SMILES CC1=C(C)C(=O)C(CC[C@](C)(O)CCCCCCCCC(F)(F)F)=C(C)C1=O

InChI Key InChIKey=DNIOGIPPEVIFNL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 594068   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Stealth Biotherapeutics

US Patent
LigandPNGBDBM594068(US11584728, Compound N | Synthesis of (R)-2,3,5-tr...)
Affinity DataIC50: 2.67E+3nMAssay Description:Briefly, reactions were carried out in Corning 96 half-well black, flat bottom assay plates and contained final concentrations of 50 μM arachido...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Stealth Biotherapeutics

US Patent
LigandPNGBDBM594068(US11584728, Compound N | Synthesis of (R)-2,3,5-tr...)
Affinity DataIC50: 2.67E+3nMAssay Description:Briefly, reactions were carried out in Corning 96 half-well black, flat bottom assay plates and contained final concentrations of 50 μM arachido...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Stealth Biotherapeutics

US Patent
LigandPNGBDBM594068(US11584728, Compound N | Synthesis of (R)-2,3,5-tr...)
Affinity DataIC50: 2.67E+3nMAssay Description:Briefly, reactions were carried out in Corning 96 half-well black, flat bottom assay plates and contained final concentrations of 50 μM arachido...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Stealth Biotherapeutics

US Patent
LigandPNGBDBM594068(US11584728, Compound N | Synthesis of (R)-2,3,5-tr...)
Affinity DataIC50: 2.67E+3nMAssay Description:Briefly, reactions were carried out in Corning 96 half-well black, flat bottom assay plates and contained final concentrations of 50 μM arachido...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetLinoleate 9S-lipoxygenase-4(Soybean)
Stealth Biotherapeutics

US Patent
LigandPNGBDBM594068(US11584728, Compound N | Synthesis of (R)-2,3,5-tr...)
Affinity DataIC50: 2.67E+3nMAssay Description:Briefly, reactions were carried out in Corning 96 half-well black, flat bottom assay plates and contained final concentrations of 50 μM arachidonic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent