BDBM594174 US11584745, Compound 16

SMILES Cc1cccc(n1)-c1cnsc1-c1ccc2nccn2c1

InChI Key InChIKey=FOXRQLADXOUTKC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 594174   

TargetTGF-beta receptor type-1(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM594174(US11584745, Compound 16)
Affinity DataIC50: 165nMAssay Description:1xkinase buffer preparation: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT. Compound preparation: The final detection concentration of the c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent