BDBM595579 US11591328, Compound 2

SMILES Cn1cc(cn1)-c1cc(Oc2ccc(NC(=O)N3CCC4(CCCCC4)C3=O)nc2)ccn1

InChI Key InChIKey=HBWUNGZZOZIRLQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 595579   

TargetMast/stem cell growth factor receptor Kit(Human)
Xiamen Biotime Biotechnology

US Patent
LigandPNGBDBM595579(US11591328, Compound 2)
Affinity DataIC50: 5.40nMAssay Description:c-Kit, PDGFRα, PDGFRβ, FLT-3:Add 5 μL of compound (10% DMSO) at 5 times the final concentration of the reaction to a 384-well plate. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Xiamen Biotime Biotechnology

US Patent
LigandPNGBDBM595579(US11591328, Compound 2)
Affinity DataIC50: 6.20nMAssay Description:CSF1R: The specific operation is as follows: Set the concentration gradient of the test compound and dilute the test compound to the working concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Xiamen Biotime Biotechnology

US Patent
LigandPNGBDBM595579(US11591328, Compound 2)
Affinity DataIC50: 1.58E+3nMAssay Description:c-Kit, PDGFRα, PDGFRβ, FLT-3:Add 5 μL of compound (10% DMSO) at 5 times the final concentration of the reaction to a 384-well plate. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
US Patent