BDBM596486 US11596639, Example 192

SMILES COc1ccc(N2C[C@@H](C)n3c(c(CCCOc4cc(C)c(Cl)c(C)c4)c4ccc(Cl)c(-c5c(C)nn(C)c5C)c34)C2=O)c2n(C)c(cc12)C(O)=O

InChI Key InChIKey=LDFJMIOFGJESIT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 596486   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM596486(US11596639, Example 192)
Affinity DataKi: <1nMAssay Description:Fluorescence Polarization Anisotropy Competition Assay. Anisotropy measurements were carried out in 384-well, black, flat-bottom plates (Greiner Bio-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
Go to US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM596486(US11596639, Example 192)
Affinity DataKi:  91nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed