BDBM597997 (E)-3-(1H-1,2,3-triazol-5-yl)methyl)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-1-(4-fluorobenzyl)-1,3,5-triazine-2,4-dione::US11612603, Compound 8

SMILES Cn1cc2cc(\N=c3/[nH]c(=O)n(Cc4cnn[nH]4)c(=O)n3Cc3ccc(F)cc3)c(Cl)cc2n1

InChI Key InChIKey=HTKHRJQWDYYJHB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 597997   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM597997(US11612603, Compound 8 | (E)-3-(1H-1,2,3-triazol-5...)
Affinity DataIC50: 350nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
Go to US Patent