BDBM598019 (E)-6-(2-methyl-2H-indazol-5-yl)imino)-3-(1-ethyl-1H-1,2,3-triazol-5-yl)methyl)-1-(4-fluorobenzyl)-1,3,5-triazine-2,4-dione::US11612603, Compound 19

SMILES CCn1nncc1Cn1c(=O)[nH]\c(=N/c2ccc3nn(C)cc3c2)n(Cc2ccc(F)cc2)c1=O

InChI Key InChIKey=RXZLXURMTDCNPW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 598019   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM598019(US11612603, Compound 19 | (E)-6-(2-methyl-2H-indaz...)
Affinity DataIC50: 350nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
Go to US Patent