BDBM598023 (E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-(1-isobutyl-1H-1,2,3-triazole-5-yl)methyl)-1-(2,4,5-trifluorobenzyl)-1,3,5-triazine-2,4-dione::US11612603, Compound 23

SMILES CC(C)Cn1nncc1Cn1c(=O)[nH]\c(=N/c2cc3cn(C)nc3cc2Cl)n(Cc2cc(F)c(F)cc2F)c1=O

InChI Key InChIKey=MTJYRYXIJVBVKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 598023   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM598023(US11612603, Compound 23 | (E)-6-(6-chloro-2-methyl...)
Affinity DataIC50: 100nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
Go to US Patent