BDBM600778 (1-(3,4-dimethylphenyl)-1H-1,2,3-triazol-4-yl)methanol::US11634391, Compound 5

SMILES Cc1ccc(cc1C)-n1cc(CO)nn1

InChI Key InChIKey=COCVVHVFRCTWBH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 600778   

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM600778((1-(3,4-dimethylphenyl)-1H-1,2,3-triazol-4-yl)meth...)
Affinity DataIC50: 730nMAssay Description:Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S cells using OPTS as substrate incubated for 40 mins by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM600778((1-(3,4-dimethylphenyl)-1H-1,2,3-triazol-4-yl)meth...)
Affinity DataIC50: 810nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent