BDBM600798 (1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-1,2,3-triazol-4-yl)methanol::US11634391, Compound 6

SMILES OCc1cn(nn1)-c1ccc2OCCOc2c1

InChI Key InChIKey=FRSRKIWOFXINSV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 600798   

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandPNGBDBM600798((1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-1,2,3-...)
Affinity DataIC50: 4.46E+4nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
Go to US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandPNGBDBM600798((1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-1,2,3-...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S cells using OPTS as substrate incubated for 40 mins by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed