BDBM600803 (1-(3-chloro-4-(trifluoromethyl)phenyl)-1H-1,2,3-triazol-4-yl)methanol::US11634391, Compound 13

SMILES OCc1cn(nn1)-c1ccc(c(Cl)c1)C(F)(F)F

InChI Key InChIKey=RMNGWKCEPYOOFD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 600803   

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandPNGBDBM600803((1-(3-chloro-4-(trifluoromethyl)phenyl)-1H-1,2,3-t...)
Affinity DataIC50: 1.72E+3nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
Go to US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandPNGBDBM600803((1-(3-chloro-4-(trifluoromethyl)phenyl)-1H-1,2,3-t...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S cells using OPTS as substrate incubated for 40 mins by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed