BDBM600809 (1-(3-chlorophenyl)-1H-1,2,3-triazol-4-yl)methanol::US11634391, Compound 21

SMILES OCc1cn(nn1)-c1cccc(Cl)c1

InChI Key InChIKey=ASILNWLZYIGPEA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 600809   

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandPNGBDBM600809((1-(3-chlorophenyl)-1H-1,2,3-triazol-4-yl)methanol...)
Affinity DataIC50: 9.49E+3nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
Go to US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandPNGBDBM600809((1-(3-chlorophenyl)-1H-1,2,3-triazol-4-yl)methanol...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S cells using OPTS as substrate incubated for 40 mins by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed