BDBM600811 (1-(2,5-dichlorophenyl)-1H-1,2,3-triazol-4-yl)methanol::US11634391, Compound 26

SMILES OCc1cn(nn1)-c1cc(Cl)ccc1Cl

InChI Key InChIKey=UWRAYFYLCHSFAA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 600811   

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandPNGBDBM600811((1-(2,5-dichlorophenyl)-1H-1,2,3-triazol-4-yl)meth...)
Affinity DataIC50: 2.55E+4nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
Go to US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandPNGBDBM600811((1-(2,5-dichlorophenyl)-1H-1,2,3-triazol-4-yl)meth...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S cells using OPTS as substrate incubated for 40 mins by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed