BDBM601089 4-[(2S)-2-(dimethylamino)-3-[3-(6-methoxypyridin-3-yl)-3-[1-(trifluoromethyl)cyclopropyl]propanamido]propyl]-2,6-difluorobenzamide ::US11634396, Compound 49

SMILES COc1ccc(cn1)C(CC(=O)NC[C@H](Cc1cc(F)c(C(N)=O)c(F)c1)N(C)C)C1(CC1)C(F)(F)F

InChI Key InChIKey=FKCODLJNXZKLEN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 601089   

TargetMu-type opioid receptor(Human)
Epiodyne

US Patent
LigandPNGBDBM601089(4-[(2S)-2-(dimethylamino)-3-[3-(6-methoxypyridin-3...)
Affinity DataIC50: 300nMAssay Description:CHO Tag-lite human mOR stable cell line from Cisbio (NCBI accession number: NM_000914.3, Bedford, Mass.) were seeded and grown to approximately 80% c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
Epiodyne

US Patent
LigandPNGBDBM601089(4-[(2S)-2-(dimethylamino)-3-[3-(6-methoxypyridin-3...)
Affinity DataIC50: 3.00E+3nMAssay Description:KOR β-Arrestin Agonist and Antagonist assays were preformed using the Tango OPRK1-bla U2OS cells from Invitrogen and purchased from ThermoFisher...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent