BDBM601211 4-((S)-2-(dimethylamino)-3-((R)-3-(2-methylpyrimidin-5-yl)-3-(1-(trifluoromethyl)cyclopropyl)propanamido)propyl)-2-fluoro-N-methylbenzamide ::US11634396, Compound 152

SMILES CNC(=O)c1ccc(C[C@@H](CNC(=O)C[C@H](c2cnc(C)nc2)C2(CC2)C(F)(F)F)N(C)C)cc1F

InChI Key InChIKey=SMCRZPSJBQBERU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 601211   

TargetMu-type opioid receptor(Human)
Epiodyne

US Patent
LigandPNGBDBM601211(US11634396, Compound 152 | 4-((S)-2-(dimethylamino...)
Affinity DataIC50: 300nMAssay Description:CHO Tag-lite human mOR stable cell line from Cisbio (NCBI accession number: NM_000914.3, Bedford, Mass.) were seeded and grown to approximately 80% c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent