BDBM601232 (R)-N-((S)-2-(dimethylamino)-3-(7-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)-3-(2-methylpyrimidin-5-yl)-3-(1-(trifluoromethyl)cyclopropyl)propanamide ::US11634396, Compound 169

SMILES CN(C)[C@H](CNC(=O)C[C@H](c1cnc(C)nc1)C1(CC1)C(F)(F)F)Cc1ccc2n(COCC[Si](C)(C)C)c(=O)oc2c1C

InChI Key InChIKey=GLQIOEJGSJXFTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 601232   

TargetMu-type opioid receptor(Human)
Epiodyne

US Patent
LigandPNGBDBM601232(US11634396, Compound 169 | (R)-N-((S)-2-(dimethyla...)
Affinity DataIC50: 300nMAssay Description:CHO Tag-lite human mOR stable cell line from Cisbio (NCBI accession number: NM_000914.3, Bedford, Mass.) were seeded and grown to approximately 80% c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent