BDBM601286 (S)-N-((S)-3-(1H-indazol-5-yl)-2-(piperidin-1-yl)propyl)-3-phenylbutanamide ::US11634396, Compound 224

SMILES C[C@@H](CC(=O)NC[C@H](Cc1ccc2n(ncc2c1)S(=O)(=O)c1ccc(C)cc1)N1CCCCC1)c1ccccc1

InChI Key InChIKey=ZIVFFHJQSOGMBW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 601286   

TargetMu-type opioid receptor(Human)
Epiodyne

US Patent
LigandPNGBDBM601286((S)-N-((S)-3-(1H-indazol-5-yl)-2-(piperidin-1-yl)p...)
Affinity DataIC50: 300nMAssay Description:CHO Tag-lite human mOR stable cell line from Cisbio (NCBI accession number: NM_000914.3, Bedford, Mass.) were seeded and grown to approximately 80% c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetDelta-type opioid receptor(Human)
Epiodyne

US Patent
LigandPNGBDBM601286((S)-N-((S)-3-(1H-indazol-5-yl)-2-(piperidin-1-yl)p...)
Affinity DataEC50: >3.00E+3nMAssay Description:The dOR cAMP agonist and antagonist assays were conducted in a manner similar as described above for the mOR assays using CHO Tag-lite human dOR stab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent