BDBM601313 (S)-3-cyclopropyl-N-((S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dimethylphenyl)propyl)-3-phenylpropanamide ::US11634396, Compound 251

SMILES CN(C)[C@H](CNC(=O)C[C@@H](C1CC1)c1ccc(Cl)cc1)Cc1c(C)cc(O)cc1C

InChI Key InChIKey=YLGSAOUFDUHTAP-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 601313   

TargetDelta-type opioid receptor(Human)
Epiodyne

US Patent
LigandPNGBDBM601313((S)-3-cyclopropyl-N-((S)-2-(dimethylamino)-3-(4-hy...)
Affinity DataEC50: <300nMAssay Description:The dOR cAMP agonist and antagonist assays were conducted in a manner similar as described above for the mOR assays using CHO Tag-lite human dOR stab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Epiodyne

US Patent
LigandPNGBDBM601313((S)-3-cyclopropyl-N-((S)-2-(dimethylamino)-3-(4-hy...)
Affinity DataIC50: 3.00E+3nMAssay Description:CHO Tag-lite human mOR stable cell line from Cisbio (NCBI accession number: NM_000914.3, Bedford, Mass.) were seeded and grown to approximately 80% c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
Epiodyne

US Patent
LigandPNGBDBM601313((S)-3-cyclopropyl-N-((S)-2-(dimethylamino)-3-(4-hy...)
Affinity DataIC50: 3.00E+3nMAssay Description:KOR β-Arrestin Agonist and Antagonist assays were preformed using the Tango OPRK1-bla U2OS cells from Invitrogen and purchased from ThermoFisher...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent