BDBM601321 (R)-N-((S)-3-(2-chloro-3-fluoro-4-methoxyphenyl)-2-(dimethylamino)propyl)-3-(pyridin-3-yl)-3-(1-(trifluoromethyl)cyclopropyl)propanamide ::US11634396, Compound 259

SMILES COc1ccc(C[C@@H](CNC(=O)C[C@H](c2cccnc2)C2(CC2)C(F)(F)F)N(C)C)c(Cl)c1F

InChI Key InChIKey=OHAGANGZUDLCPH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 601321   

TargetMu-type opioid receptor(Human)
Epiodyne

US Patent
LigandPNGBDBM601321((R)-N-((S)-3-(2-chloro-3-fluoro-4-methoxyphenyl)-2...)
Affinity DataIC50: 300nMAssay Description:CHO Tag-lite human mOR stable cell line from Cisbio (NCBI accession number: NM_000914.3, Bedford, Mass.) were seeded and grown to approximately 80% c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent