BDBM602342 (R)-4-(4-((1-(3-(1,1-difluoro-3-(1- isopropylazetidin-3-yl)propyl)-2- fluorophenyl)ethyl)amino)-7-methoxy- 2-methylpyrido[2,3-d]pyrimidin-6- yl)tetrahydro-2H- thiopyran 1,1-dioxide::US11648254, Compound 238

SMILES COc1nc2nc(C)nc(N[C@H](C)c3cccc(c3F)C(F)(F)CCC3CN(C3)C(C)C)c2cc1C1CCS(=O)(=O)CC1

InChI Key InChIKey=GPOVWYYFPCVRKY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602342   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602342(US11648254, Compound 238 | (R)-4-(4-((1-(3-(1,1-di...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent