BDBM603698 US11654147, Compound 3

SMILES NC(=O)c1ccc(-c2cnn3cc(cnc23)N2CCN(CC2)C2CCNCC2)c2ccccc12

InChI Key InChIKey=AALVXGCMOJVFCP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 603698   

TargetActivin receptor type-1(Human)
The Brigham and Women'S Hospital

US Patent
LigandPNGBDBM603698(US11654147, Compound 3)
Affinity DataIC50: 13nMAssay Description:In this reporter gene cell based ALK2 and TGFβ assay, the C2Cl2 cell line was employed for the measurement of ALK2 activity, using a BRE-Luc SMA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent