BDBM603861 US11654147, Compound 311::US11654147, Compound 337

SMILES CN1CCN(CC1)C1CN(C1)c1cnc2c(cnn2c1)-c1cc(C)nc2c(F)cc(F)cc12

InChI Key InChIKey=JMSVAFIWODQZIG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 603861   

TargetActivin receptor type-1(Human)
The Brigham and Women'S Hospital

US Patent
LigandPNGBDBM603861(US11654147, Compound 311 | US11654147, Compound 33...)
Affinity DataIC50: 9nMAssay Description:In this reporter gene cell based ALK2 and TGFβ assay, the C2Cl2 cell line was employed for the measurement of ALK2 activity, using a BRE-Luc SMA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent

TargetActivin receptor type-1(Human)
The Brigham and Women'S Hospital

US Patent
LigandPNGBDBM603861(US11654147, Compound 311 | US11654147, Compound 33...)
Affinity DataIC50: 33nMAssay Description:In this reporter gene cell based ALK2 and TGFβ assay, the C2Cl2 cell line was employed for the measurement of ALK2 activity, using a BRE-Luc SMA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent