BDBM605539 US11673888, Example 4.01

SMILES CC(C)C(=O)Nc1cc(C#N)c(Cl)cc1COC(=O)N1Cc2nc(oc2C1)C(=O)N1CCc2c(O)noc2C1

InChI Key InChIKey=QVSZDAMSAMFXNG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 605539   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM605539(US11673888, Example 4.01)
Affinity DataIC50: 7nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
Go to US Patent