BDBM605793 US11673901, Compound 63

SMILES CNC(=O)O[C@H]1C[C@@H](N)C2(C1)CCN(CC2)c1nc(C)c(-c2cccc(Cl)c2Cl)c2nccn12

InChI Key InChIKey=AALFDGAODHKGSX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 605793   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandPNGBDBM605793(US11673901, Compound 63)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent