BDBM60580 3-(4-Aminosulfonylphenylamino)-5-methyl-2-(4-trifluoromethylphenyl)-4-thiazol-idinone (8e)

SMILES CC1SC(N(Nc2ccc(cc2)S(N)(=O)=O)C1=O)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=MDPBHEUQSHAWOM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 60580   

TargetProstaglandin G/H synthase 1(Sheep)
Beni-Suef University

LigandPNGBDBM60580(3-(4-Aminosulfonylphenylamino)-5-methyl-2-(4-trifl...)
Affinity DataIC50: 1.18E+4nMAssay Description:The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandPNGBDBM60580(3-(4-Aminosulfonylphenylamino)-5-methyl-2-(4-trifl...)
Affinity DataIC50: 3.40E+3nMAssay Description:The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed