BDBM605945 US11680060, Example 186::US11680060, Example 187::US11680060, Example 6

SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)N(C)C)[C@@H]1COC1CCC2(CC2C1)c1ncccn1

InChI Key InChIKey=AMJLPIKYQOFNQO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 605945   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM605945(US11680060, Example 6 | US11680060, Example 187 | ...)
Affinity DataIC50: 0.940nMAssay Description:IP-One, Cisbio, cat #621PAPEC, is a commercially available assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM605945(US11680060, Example 6 | US11680060, Example 187 | ...)
Affinity DataIC50: 2.10nMAssay Description:IP-One, Cisbio, cat #621PAPEC, is a commercially available assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM605945(US11680060, Example 6 | US11680060, Example 187 | ...)
Affinity DataIC50: 142nMAssay Description:IP-One, Cisbio, cat #621PAPEC, is a commercially available assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent