BDBM606340 3-[1-(2-Fluoro-6-methyl-phenyl)piperidin-4-yl]-1-[2-(tetrahydro-pyran-4-yloxy)-benzyl]-3,4-dihydro-1H-quinazolin-2-one ::US11685729, Example 53

SMILES Cc1cccc(F)c1N1CCC(CC1)N1Cc2ccccc2N(Cc2ccccc2OC2CCOCC2)C1=O

InChI Key InChIKey=GOWOHJGJJOZBMH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 606340   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM606340(3-[1-(2-Fluoro-6-methyl-phenyl)piperidin-4-yl]-1-[...)
Affinity DataIC50: 32nMAssay Description:Adherent cells (CHO-K1 C5AR1 beta-arrestin cell line, DiscoverX, CA USA) are washed with PBS, detached by incubation with Dissociation Buffer (Gibco ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent