BDBM606349 1-(2-Cyclopropyl-benzyl)-3-[1-(2-fluoro-6-methyl-phenyl)-piperidin-4-yl]-3,4-dihydro-1H-quinazolin-2-one::US11685729, Example 56

SMILES Cc1cccc(F)c1N1CCC(CC1)N1Cc2ccccc2N(Cc2ccccc2C2CC2)C1=O

InChI Key InChIKey=FOBWPBOYCGBEGR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 606349   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM606349(1-(2-Cyclopropyl-benzyl)-3-[1-(2-fluoro-6-methyl-p...)
Affinity DataIC50: 28nMAssay Description:Adherent cells (CHO-K1 C5AR1 beta-arrestin cell line, DiscoverX, CA USA) are washed with PBS, detached by incubation with Dissociation Buffer (Gibco ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent