BDBM607616 US11691962, Compound 1-13

SMILES CC[C@@H](NC(=O)N1[C@@H]([C@@H](Cc2ccnc(N)c2)C1=O)C(=O)N(C)c1nccn1C)c1ccccc1

InChI Key InChIKey=BSISHEWSCGEKCQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 607616   

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandPNGBDBM607616(US11691962, Compound 1-13)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandPNGBDBM607616(US11691962, Compound 1-13)
Affinity DataIC50: 10nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed