BDBM607832 US11691963, Example I-10

SMILES COc1ccc(Cn2cc(Cc3ccc(Nc4nc5ccc(Oc6ccnc(NC(C)=O)c6)cc5n4C)cc3C(F)(F)F)cn2)cc1

InChI Key InChIKey=RWLRMMXYVKJRAW-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 607832   

TargetTyrosine-protein kinase JAK2 [Y1007F,Y1008F](Human)
Ajax Therapeutics

US Patent
LigandPNGBDBM607832(US11691963, Example I-10)
Affinity DataKd:  525nMAssay Description:JAK2 (JH1domain-catalytic, Y1007F,Y1008F) kinase was expressed as N-terminal fusion to the DNA binding domain of NFkB in transiently transfected HEK2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
Go to US Patent