BDBM607845 US11691963, Example I-22

SMILES CC(=O)Nc1ccc(Oc2cnc3n(C)c(Nc4cc(n(n4)[C@H]4CCOC4)C(C)(C)C)nc3c2)cn1

InChI Key InChIKey=GYOCAUHMNLPWJA-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 607845   

TargetTyrosine-protein kinase JAK2 [Y1007F,Y1008F](Human)
Ajax Therapeutics

US Patent
LigandPNGBDBM607845(US11691963, Example I-22)
Affinity DataKd: <10nMAssay Description:JAK2 (JH1domain-catalytic, Y1007F,Y1008F) kinase was expressed as N-terminal fusion to the DNA binding domain of NFkB in transiently transfected HEK2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
Go to US Patent