BDBM607852 US11691963, Example I-29

SMILES CCCCO[C@H]1C[C@@H](C1)n1nc(Nc2nc3ccc(Oc4ccnc(NC(C)=O)c4)cc3n2C)cc1C(C)(C)C

InChI Key InChIKey=MRQANPPAQFPPSA-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 607852   

TargetTyrosine-protein kinase JAK2 [Y1007F,Y1008F](Human)
Ajax Therapeutics

US Patent
LigandPNGBDBM607852(US11691963, Example I-29)
Affinity DataKd: <10nMAssay Description:JAK2 (JH1domain-catalytic, Y1007F,Y1008F) kinase was expressed as N-terminal fusion to the DNA binding domain of NFkB in transiently transfected HEK2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
Go to US Patent