BDBM608821 (6-((2-amino-3-chloropyridin-4-yl)thio)-3-(4-amino-4-methylpiperidin-1-yl)pyrazin-2-yl)methanol ::US11702411, Compound 4

SMILES CC1(N)CCN(CC1)c1ncc(Sc2ccnc(N)c2Cl)nc1CO

InChI Key InChIKey=GQYKVZZNIVPNST-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608821   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandPNGBDBM608821((6-((2-amino-3-chloropyridin-4-yl)thio)-3-(4-amino...)
Affinity DataIC50: 50nMAssay Description:The inhibition of SHP2 by compounds of the present disclosure (concentrations varying from 0.00005-10 μM) was monitored using an assay in which ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
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