BDBM60970 Ethoxzolamide (EZA)

SMILES CCOc1ccc2N=CC(CS(N)(=O)=O)Sc2c1

InChI Key InChIKey=BSIVPMYWAXTFRA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 60970   

TargetCarbonic anhydrase 2(Human)
Kirklareli University

LigandPNGBDBM60970(Ethoxzolamide (EZA))
Affinity DataKi:  11nM ΔG°:  -10.8kcal/molepH: 7.5 T: 2°CAssay Description:Phenol red (at a concentration of 0.2 mM) has been used as indicator, working at the absorbance maximum of 557 nm, with 10 mM Tris-HCl (pH 7.5) as bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Kirklareli University

LigandPNGBDBM60970(Ethoxzolamide (EZA))
Affinity DataKi:  30nM ΔG°:  -10.3kcal/molepH: 7.5 T: 2°CAssay Description:Phenol red (at a concentration of 0.2 mM) has been used as indicator, working at the absorbance maximum of 557 nm, with 10 mM Tris-HCl (pH 7.5) as bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Kirklareli University

LigandPNGBDBM60970(Ethoxzolamide (EZA))
Affinity DataKi:  50nM ΔG°:  -9.95kcal/molepH: 7.5 T: 2°CAssay Description:Phenol red (at a concentration of 0.2 mM) has been used as indicator, working at the absorbance maximum of 557 nm, with 10 mM Tris-HCl (pH 7.5) as bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed