BDBM612315 BDBM612401::BDBM612402::N'-(1,2,3,5,6,7-hexahydro-5-indacen- 4-ylcarbamoyl)-1-isopropyl-1H- pyrazole-3-sulfonimidamide

SMILES CC(C)n1ccc(n1)S(N)(=O)=NC(=O)Nc1c2CCCc2cc2CCCc12

InChI Key InChIKey=MMPSDZURSJKDME-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 612315   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
IFM Therapeutics GmbH

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 612315BDBM612315(BDBM612401 | BDBM612402 | N'-(1,2,3,5,6,7-hexahydr...)
Affinity DataIC50: 137nMAssay Description:Antagonist activity against NLRP3 in PMA-primed human THP-1 cells assessed as inhibition of gramicidin-induced IL-1beta release measured after 1 hr i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed