BDBM612331 4-(2-hydroxypropan-2-yl)-5-methyl- N'-((1-methyl-1,2,3,5,6,7-hexahydro- s-indacen-4-yl)carbamoyl)furan-2- sulfonimidamide::BDBM612435::BDBM612437::BDBM612612::BDBM612613::US11724992, Example 32

SMILES CC1CCc2cc3CCCc3c(NC(=O)N=S(N)(=O)c3cc(c(C)o3)C(C)(C)O)c12

InChI Key InChIKey=OTIZLUYZMVTQOG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 612331   

LigandPNGBDBM612331(BDBM612612 | 4-(2-hydroxypropan-2-yl)-5-methyl- N'...)
Affinity DataIC50: 24nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM612331(BDBM612612 | 4-(2-hydroxypropan-2-yl)-5-methyl- N'...)
Affinity DataIC50: 24nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM612331(BDBM612612 | 4-(2-hydroxypropan-2-yl)-5-methyl- N'...)
Affinity DataIC50: 120nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM612331(BDBM612612 | 4-(2-hydroxypropan-2-yl)-5-methyl- N'...)
Affinity DataIC50: 600nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM612331(BDBM612612 | 4-(2-hydroxypropan-2-yl)-5-methyl- N'...)
Affinity DataIC50: 3.00E+3nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent