BDBM612512 (R)-or (S)- N'-(8-fluoro-1,2,3,5,6,7-hexahydro- s-indacen-4-ylcarbamoyl)-2-(2- hydroxypropan-2-yl)thiazole-5- sulfonimidamide::US11724992, Compound 106::US11724992, Example 44

SMILES CC(C)(O)c4ncc(S(N)(=O)=NC(=O)Nc3c1CCCc1c(F)c2CCCc23)s4

InChI Key InChIKey=GGWUCSGCICBGCE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 612512   

LigandChemical structure of BindingDB Monomer ID 612512BDBM612512((R)-or (S)- N'-(8-fluoro-1,2,3,5,6,7-hexahydro- s-...)
Affinity DataIC50: 24nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent