BDBM612576 BDBM612669::BDBM612670::N'-(1,2,3,5,6,7-hexahydro- s-indacen-4-ylcarbamoyl)- 4-(2-hydroxypropan-2-yl)- 5-methylthiazole-2- sulfonimidamide::US11724992, Example 265

SMILES Cc1sc(nc1C(C)(C)O)S(N)(=O)=NC(=O)Nc1c2CCCc2cc2CCCc12

InChI Key InChIKey=ISRWDXUEVBUTSL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 612576   

LigandPNGBDBM612576(N'-(1,2,3,5,6,7-hexahydro- s-indacen-4-ylcarbamoyl...)
Affinity DataIC50: 24nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM612576(N'-(1,2,3,5,6,7-hexahydro- s-indacen-4-ylcarbamoyl...)
Affinity DataIC50: 120nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM612576(N'-(1,2,3,5,6,7-hexahydro- s-indacen-4-ylcarbamoyl...)
Affinity DataIC50: 600nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent