BDBM612846 N-[[2-[[(1- hydroxycyclobutyl) methylamino] methyl]-1H- indol-6- yl]methyl]-4- oxo-pyrido[1,2- a]pyrimidine-2- carboxamide::US11725010, Example 4

SMILES OC1(CNCc2cc3ccc(CNC(=O)c4cc(=O)n5ccccc5n4)cc3[nH]2)CCC1

InChI Key InChIKey=PLKIRMUAUZWMBC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 612846   

TargetN6-adenosine-methyltransferase catalytic/non-catalytic subunit(Human)
Storm Therapeutics

US Patent

LigandBDBM612846(US11725010, Example 4 | N-[[2-[[(1- hydroxycyclobu...)Copy SMILESCopy InChI

Affinity DataIC50: 6.10nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/23/2023
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL