BDBM6134 8-[(2-bromo-4-chloro-5-methoxyphenyl)amino]-3H-imidazo[4,5-g]quinoline-7-carbonitrile::Anilinoimidazo[4,5-g]quinoline 11b

SMILES COc1cc(Nc2c(cnc3cc4nc[nH]c4cc23)C#N)c(Br)cc1Cl

InChI Key InChIKey=CWXPNWXLJJVHRY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6134   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM6134(8-[(2-bromo-4-chloro-5-methoxyphenyl)amino]-3H-imi...)
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2005
Entry Details Article
PubMed