BDBM613977 US11739089, Compound 11

SMILES COc1cc(NC(=O)c2ccc3c(c2)oc2ccccc2c3=O)c(cc1OC)-c1nnn(n1)-c1ccc(CCN2CCc3cnccc3C2)cc1

InChI Key InChIKey=OEPGCQPBNALOQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 613977   

TargetCytochrome P450 3A4(Human)
Athenex

US Patent
LigandPNGBDBM613977(US11739089, Compound 11)
Affinity DataIC50: 375nMAssay Description:Test compounds, DMSO (negative control), and ketoconazole (positive control) were diluted to 4× final concentrations in water. The standard final Com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2023
Entry Details
Go to US Patent