BDBM614839 A7-17-1 rel-2-((3R,4R)-4-(((6- (cyclopropyl((2- (trifluoromethyl)pyrimidin-5- yl)methyl)amino)-5- fluoropyrimidin-4- yl)amino)methyl)-3- hydroxypiperidin-1-yl)acetamide 1st eluting isomer::US20230271937, Example A7-17-1

SMILES NC(=O)CN1CC[C@H](CNc2ncnc(N(Cc3cnc(nc3)C(F)(F)F)C3CC3)c2F)[C@@H](O)C1

InChI Key InChIKey=OLKMOTJGOGDQNS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614839   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614839(US20230271937, Example A7-17-1 | A7-17-1 rel-2-((3...)
Affinity DataEC50:  40nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent