BDBM616075 US20230271964, Example 1-32

SMILES Cc1nc(Cn2nc3c(-c4cc(C)nc(C)c4)c(nc(N)n3c2=O)-c2ccc(F)cc2)c(C)o1

InChI Key InChIKey=MJISJGGKEFUILP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 616075   

TargetAdenosine receptor A2a(Human)
Astrazeneca

US Patent
LigandPNGBDBM616075(US20230271964, Example 1-32)
Affinity DataKi:  0.316nMAssay Description:Inhibition binding assays were performed using 0.2 µg of membranes prepared from HEK293 cells infected with BacMam human adenosine A2A receptor or 1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
Astrazeneca

US Patent
LigandPNGBDBM616075(US20230271964, Example 1-32)
Affinity DataKi:  100nMAssay Description:Inhibition binding assays were performed using 0.2 µg of membranes prepared from HEK293 cells infected with BacMam human adenosine A2A receptor or 1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent