BDBM616837 6-(3-chloro-2-fluorobenzyl)-5-methyl-2-((4-phenylpiperazin-1-yl)methyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7(3H)-one ::US20230279008, Compound 6

SMILES Cc1[nH]c2nc(CN3CCN(CC3)c3ccccc3)nn2c(=O)c1Cc1cccc(Cl)c1F

InChI Key InChIKey=LGJQAFSACXQDAX-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 616837   

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616837(US20230279008, Compound 6 | 6-(3-chloro-2-fluorobe...)
Affinity DataIC50: 0.0200nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616837(US20230279008, Compound 6 | 6-(3-chloro-2-fluorobe...)
Affinity DataEC50:  300nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent