BDBM616839 6-(3-fluorobenzyl)-5-methyl-2-(1-(4-phenylpiperazin-1-yl)ethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one ::US20230279008, Compound 10

SMILES CC(N1CCN(CC1)c1ccccc1)c1nc2[nH]c(C)c(Cc3cccc(F)c3)c(=O)n2n1

InChI Key InChIKey=YFUPHQICKXJCSB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 616839   

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616839(US20230279008, Compound 10 | 6-(3-fluorobenzyl)-5-...)
Affinity DataIC50: 7.90nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616839(US20230279008, Compound 10 | 6-(3-fluorobenzyl)-5-...)
Affinity DataEC50:  77.4nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent