BDBM616842 5-methyl-2-(1-(4-phenylpiperazin-1-yl)ethyl)-6-(3-(trifluoromethyl)benzyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one ::US20230279008, Compound 13

SMILES CC(N1CCN(CC1)c1ccccc1)c1nc2[nH]c(C)c(Cc3cccc(c3)C(F)(F)F)c(=O)n2n1

InChI Key InChIKey=YZTZMAWWIGVSJQ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 616842   

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616842(US20230279008, Compound 13 | 5-methyl-2-(1-(4-phen...)
Affinity DataIC50: 61.9nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616842(US20230279008, Compound 13 | 5-methyl-2-(1-(4-phen...)
Affinity DataEC50:  19.2nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent