BDBM616852 6-(3-chlorobenzyl)-5-methyl-2-((1-phenylpiperidin-4-ylidene)methyl)-[1,2,4]triazolo[1,5-a] pyrimidin-7(4H)-one ::US20230279008, Compound 34

SMILES Cc1[nH]c2nc(C=C3CCN(CC3)c3ccccc3)nn2c(=O)c1Cc1cccc(Cl)c1

InChI Key InChIKey=ZRGPISOCWCPMBG-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 616852   

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616852(US20230279008, Compound 34 | 6-(3-chlorobenzyl)-5-...)
Affinity DataIC50: 60.2nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616852(US20230279008, Compound 34 | 6-(3-chlorobenzyl)-5-...)
Affinity DataEC50:  427nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent