BDBM616855 6-isopropyl-2-((2-oxo-2-(4-(thiazol-2-yl)piperazin-1-yl)ethyl)thio)pyrimidin-4(3H)-one ::US20230279008, Compound 48

SMILES CC(C)c1cc(=O)[nH]c(SCC(=O)N2CCN(CC2)c2nccs2)n1

InChI Key InChIKey=AUOSOXFMDPXGJU-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 616855   

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616855(US20230279008, Compound 48 | 6-isopropyl-2-((2-oxo...)
Affinity DataIC50: 86.1nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616855(US20230279008, Compound 48 | 6-isopropyl-2-((2-oxo...)
Affinity DataEC50:  129nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent