BDBM616856 (R)-6-isopropyl-2-((2-(4-(2-methoxyphenyl)-3-methylpiperazin-1-yl)-2-oxoethyl)thio)pyrimidin-4(3H)-one ::US20230279008, Compound 53

SMILES COc1ccccc1N1CCN(C[C@H]1C)C(=O)CSc1nc(cc(=O)[nH]1)C(C)C

InChI Key InChIKey=LSMUGNLKPZSBHC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 616856   

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616856(US20230279008, Compound 53 | (R)-6-isopropyl-2-((2...)
Affinity DataIC50: 52.5nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616856(US20230279008, Compound 53 | (R)-6-isopropyl-2-((2...)
Affinity DataEC50:  207nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent