BDBM616858 2-((2-(4-(2-ethoxyphenyl)piperazin-1-yl)-2-oxoethyl)thio)-6-isopropylpyrimidin-4(3H)-one ::US20230279008, Compound 63

SMILES CCOc1ccccc1N1CCN(CC1)C(=O)CSc1nc(cc(=O)[nH]1)C(C)C

InChI Key InChIKey=SFRYEOVAIYVWHW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 616858   

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616858(US20230279008, Compound 63 | 2-((2-(4-(2-ethoxyphe...)
Affinity DataIC50: 81.8nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616858(US20230279008, Compound 63 | 2-((2-(4-(2-ethoxyphe...)
Affinity DataEC50:  164nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent