BDBM617430 US20230285377, Example 18

SMILES C[C@H](NC(=O)c1cccc(Cl)c1)c1cc(no1)-c1ccnc(c1)C1CC1

InChI Key InChIKey=WZYHJMVGKIYSPQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 617430   

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617430(US20230285377, Example 18)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent